Overview |
bs-25013R-Cy3 |
ATG5/APG5L Polyclonal Antibody, Cy3 Conjugated |
WB |
Mouse, Rat |
Human, Dog, Cow, Pig |
Specifications |
Cy3 |
Rabbit |
KLH conjugated synthetic peptide derived from human ATG5/APG5L |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
9474 |
Q9H1Y0 |
Cytoplasm |
APG 5; APG 5L; APG5; APG5 autophagy 5 like; APG5 like; APG5-like; Apoptosis specific protein; Apoptosis-specific protein; ASP; ATG 5; ATG5; ATG5 autophagy related 5 homolog; Autophagy protein 5; hAPG5; Homolog of S Cerevisiae autophagy 5; ATG5_HUMAN. |
Required for autophagy. Conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed (By similarity). May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. |
Application Dilution |
WB |
1:300-5000 |