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DLK1 Polyclonal Antibody, Cy3 Conjugated

Applications

  • WB
  • FCM
  • IF(IHC-P)

Reactivity

  • Human
  • Mouse
  • Rat
  • Sheep

Predicted Reactivity

  • Pig
  • Rabbit
Overview
Catalog # bs-2423R-Cy3
Product Name DLK1 Polyclonal Antibody, Cy3 Conjugated
Applications WB, FCM, IF(IHC-P)
Reactivity Human, Mouse, Rat, Sheep
Predicted Reactivity Pig, Rabbit
Specifications
Conjugation Cy3
Host Rabbit
Source KLH conjugated synthetic peptide derived from mouse DLK1
Immunogen Range 251-350/383
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 8788
Swiss Prot P80370
Subcellular location Cell membrane
Synonyms DLK; FA1; ZOG; pG2; DLK-1; PREF1; Delta1; Pref-1; Protein delta homolog 1; DLK1
Background This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass. [provided by RefSeq, Mar 2010].
Application Dilution
WB 1:300-5000
FCM 1:20-100
IF(IHC-P) 1:50-200