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CD47/MER6 Polyclonal Antibody, PE Conjugated

Applications

  • WB
  • FCM

Reactivity

  • Mouse
  • Rat

Predicted Reactivity

  • Human
  • Rabbit
Overview
Catalog # bs-2386R-PE
Product Name CD47/MER6 Polyclonal Antibody, PE Conjugated
Applications WB, FCM
Reactivity Mouse, Rat
Predicted Reactivity Human, Rabbit
Specifications
Conjugation PE
Host Rabbit
Source KLH conjugated synthetic peptide derived from human CD47/MER6
Immunogen Range 241-323/323
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 961
Swiss Prot Q08722
Subcellular location Cell membrane
Synonyms IAP; OA3; MER6; Leukocyte surface antigen CD47; Antigenic surface determinant protein OA3; Integrin-associated protein; Protein MER6; CD47
Background Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.
Application Dilution
WB 1:300-5000
FCM 1:20-100