Cytochrome C Polyclonal Antibody, Cy5.5 Conjugated
Applications
Reactivity
Predicted Reactivity
Overview | |
Catalog # | bs-22900R-Cy5.5 |
Product Name | Cytochrome C Polyclonal Antibody, Cy5.5 Conjugated |
Applications | WB |
Reactivity | Mouse, Rat |
Predicted Reactivity | Cow, Pig, Horse |
Specifications | |
Conjugation | Cy5.5 |
Host | Rabbit |
Source | Cytochrome c from bovine heart |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target | |
Gene ID | 54205 |
Swiss Prot | P99999 |
Subcellular location | Cytoplasm, Cell membrane |
Synonyms | CytC; CYC; CYCS; Cytochrome c somatic; HCS; CYC_HUMAN; CYC_MOUSE; Cytochrome-c; MSA06; THC4. |
Background | Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases. |
Application Dilution | |
WB |