Overview |
bs-2201R-Biotin |
GEF H1 (Ser886) Polyclonal Antibody, Biotin Conjugated |
WB, ELISA, IHC-P, IHC-F |
Human |
Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit |
Specifications |
Biotin |
Rabbit |
KLH conjugated synthetic phosphopeptide derived from human Arhgef2 around the phosphorylation site of Ser886 |
Ser886 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
9181 |
Cytoplasm, Cell membrane |
GEF H1phospho S886; Arhgef2Ser886; Lbcl1; Lfc; mKIAA0651; AA408978; ARHG2; ARHGEF 2; ARHGEF-2; ARHGEF2; GEF; GEF H1; GEF-H1; GEFH1; LFP40; MGC95068; P40; Prolerating cell nucleolar antigen p40; Protein GEF-H1; rho/rac guanine nucleotide exchange factor GEF 2; rho/rac guanine nucleotide exchange factor 2; rho/rac guanine nucleotide exchange factor. |
GEF-H1 is a Rho guanine nucleotide exchange factor that localizes to microtubules and regulates Rho activity in response to microtubule destabilization (loss of interaction between GEF-H1 and microtubules leads to activation of Rho). This protein has also been shown to localize to tight junctions and modulate polarized cell permeability. |
Application Dilution |
WB |
1:300-5000 |
ELISA |
1:500-1000 |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |