Overview |
bs-2075R-HRP |
Heme oxygenase 1 Polyclonal Antibody, HRP Conjugated |
WB, ELISA, IHC-P, IHC-F |
Human, Mouse, Rat, Pig, Chicken |
Dog, Cow, Sheep, Horse, Rabbit, Guinea Pig |
Specifications |
HRP |
Rabbit |
KLH conjugated synthetic peptide derived from human Heme Oxygenase 1 |
101-200/288 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
3162 |
P09601 |
Cytoplasm |
HO-1; HSP32; HMOX1D; bK286B1; HMOX1; HO; HO1 |
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis. |
Application Dilution |
WB |
1:300-5000 |
ELISA |
1:500-1000 |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |