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FAIM3 Polyclonal Antibody, PE-Cy5.5 Conjugated

Applications

  • WB

Reactivity

  • Human
Overview
Catalog # bs-20130R-PE-Cy5.5
Product Name FAIM3 Polyclonal Antibody, PE-Cy5.5 Conjugated
Applications WB
Reactivity Human
Specifications
Conjugation PE-Cy5.5
Host Rabbit
Source KLH conjugated synthetic peptide derived from human FAIM3
Immunogen Range 51-150/390
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 9214
Swiss Prot O60667
Subcellular location Secreted, Cell membrane
Synonyms TOSO; FAIM3; Fas apoptotic inhibitory molecule 3; Regulator of Fas-induced apoptosis Toso
Background May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.
Application Dilution
WB 1:300-5000