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Angiotensin 1 Polyclonal Antibody, RBITC Conjugated

Applications

  • WB
  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Reactivity

  • Mouse

Predicted Reactivity

  • Human
  • Rat
  • Dog
  • Sheep
  • Horse
Overview
Catalog # bs-1707R-RBITC
Product Name Angiotensin 1 Polyclonal Antibody, RBITC Conjugated
Applications WB, IF(IHC-P), IF(IHC-F), IF(ICC)
Specificity Immunogen used for this antibody is DRVYIHPFHL, corresponding to amino acids 34-43 of human Angiotensinogen.
Reactivity Mouse
Predicted Reactivity Human, Rat, Dog, Sheep, Horse
Specifications
Conjugation RBITC
Host Rabbit
Source KLH conjugated synthetic peptide of human Angiotensin I
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 183
Subcellular location Secreted
Synonyms AGT; Alpha 1 antiproteinase antitrypsin; Ang I; Ang II; Ang III; Angiotensin 1; Angiotensin; Angiotensin I; Angiotensin II; Angiotensin-2; Angiotensin III; Angiotensin-3; Angiotensinogen; Angiotensinogen serpin peptidase inhibitor clade A member 8; ANGT_HUMAN; Angiotensin 1-10; Angiotensin 1-8; ANHU; Des-Asp[1]-angiotensin II; FLJ92595; FLJ97926; OTTHUMP00000035878; Pre angiotensinogen; Serine or cysteine proteinase inhibitor; Serpin A8; Serpin peptidase inhibitor, clade A, member 8; SERPINA8.
Background Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. Angiotensin-2: acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and secrete aldosterone. Angiotensin-3: stimulates aldosterone release. Angiotensin 1-7: is a ligand for the G-protein coupled receptor MAS1. Has vasodilator and antidiuretic effects. Has an antithrombotic effect that involves MAS1-mediated release of nitric oxide from platelets.
Application Dilution
WB 1:300-5000
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

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