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phospho-HEF1 (Ser369) Polyclonal Antibody, HRP Conjugated

Applications

  • WB

Reactivity

  • Human
Overview
Catalog # bs-16681r-hrp-100ul
Product Name phospho-HEF1 (Ser369) Polyclonal Antibody, HRP Conjugated
Applications WB
Reactivity Human
Specifications
Conjugation HRP
Host Rabbit
Source KLH conjugated synthesised phosphopeptide derived from human HEF1 around the phosphorylation site of Ser369
Modification Site Ser369
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 4739
Swiss Prot Q14511
Subcellular location Cytoplasm
Synonyms HEF1 (phospho S369); p-HEF1 (phospho S369); Cas like docking; Cas scaffolding protein family member 2; CAS-L; CAS2; CasL; CASL_HUMAN; CASS2; Crk associated substrate related; Crk associated substrate related protein; CRK-associated substrate-related protein; dJ49G10.2 (Enhancer of Filamentation 1 (HEF1)); dJ49G10.2; dJ761I2.1 (enhancer of filamentation (HEF1)); dJ761I2.1; Enhancer of filamentation 1; Enhancer of filamentation 1 p55; HEF 1; HEF1
Background The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Application Dilution
WB 1:300-5000