Overview |
bs-1666R |
CCL21/6Ckine Polyclonal Antibody |
WB, ELISA, IHC-P, IF(IHC-P) |
Mouse, Rat |
Human, Dog, Pig, Horse, Rabbit |
Specifications |
Unconjugated |
Rabbit |
KLH conjugated synthetic peptide derived from human CCL21 |
24-134/134 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target |
6366 |
O00585 |
Secreted |
ECL; SLC; CKb9; TCA4; 6Ckine; SCYA21; C-C motif chemokine 21; Beta-chemokine exodus-2; Secondary lymphoid-tissue chemokine; Small-inducible cytokine A21; CCL21; UNQ784/PRO1600 |
Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. |
Application Dilution |
WB |
1:300-5000 |
ELISA |
1:500-1000 |
IHC-P |
1:200-400 |
IF(IHC-P) |
1:50-200 |