Overview |
bs-15518R-HRP |
IFITM5 Polyclonal Antibody, HRP Conjugated |
WB, ELISA, IHC-P, IHC-F |
Human |
Specifications |
HRP |
Rabbit |
KLH conjugated synthetic peptide derived from human IFITM5 |
1-100/132 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
Cell membrane |
Bone-restricted interferon-induced transmembrane protein-like protein; BRIL; Fragilis4; Hrmp1; ITM5; M5_HUMAN; Interferon-induced transmembrane protein 5. |
IFITM5 is a membrane protein thought to play a role in bone mineralization. This gene is located on chromosome 11 in a cluster of related genes which are induced by interferon, however, this gene has not been shown to be interferon inducible. A similar gene, located in a gene cluster on mouse chromosome 7, is a member of the interferon-inducible fragilis gene family. The mouse gene encodes a transmembrane protein described as participating in germ cell competence. A mutation in the 5' UTR of this gene has been associated with osteogenesis imperfecta type V (PMID: 22863190, 22863195). |
Application Dilution |
WB |
1:300-5000 |
ELISA |
1:500-1000 |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |