Overview |
bs-15294R-Cy3 |
C8orf47 Polyclonal Antibody, Cy3 Conjugated |
WB |
Human |
Specifications |
Cy3 |
Rabbit |
KLH conjugated synthetic peptide derived from human C8orf47 |
1-100/374 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
203111 |
Cytoplasm, Nucleus |
C8orf47; CH047_HUMAN; Chromosome 8 open reading frame 47; Uncharacterized protein C8orf47. |
Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome. The C8orf47 gene product has been provisionally designated C8orf47 pending further characterization. |
Application Dilution |
WB |
1:300-5000 |