| Overview |
| bs-1429R |
| GNAI3 Polyclonal Antibody |
| ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC) |
| Human, Mouse, Rat, Dog, Cow, Pig, Horse, Chicken |
| Specifications |
| Unconjugated |
| Rabbit |
| KLH conjugated synthetic peptide derived from human GNAI3 |
| 241-354/354 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Target |
| 2773 |
| Cytoplasm, Cell membrane |
| GAI3; 87U6; FLJ26559; G protein alpha inhibiting 3; Gi alpha 3; Gi alpha-3; GNAI3; GNAI3_HUMAN; Guanine nucleotide binding protein G protein alpha inhibiting activity polypeptide 3; Guanine nucleotide binding protein Gk alpha subunit; Guanine nucleotide-binding protein Gk subunit alpha; OTTHUMP00000013368; Gnai3; Guanine nucleotide binding protein G protein, alpha inhibiting 3; G Alpha i-3. |
| GAI3 is the a subunit of inhibitory trimeric G protein (Gi), which inhibits adenylate cyclase once its G protein coupled receptors (GPCR) such as a2 adrenergic receptors are activated. GAI3 can be inactivated by pertussis toxin. Guanine nucleotide binding proteins are involved as modulators or transducers in various transmembrane signaling systems. G(k) is the stimulatory G protein of receptor regulated K(+) channels. |
| Application Dilution |
| ELISA |
1:500-1000 |
| IHC-P |
1:200-400 |
| IHC-F |
1:100-500 |
| IF(IHC-P) |
1:50-200 |
| IF(IHC-F) |
1:50-200 |
| IF(ICC) |
1:50-200 |
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