Overview |
bs-14070R-PE-Cy7 |
Crry Polyclonal Antibody, PE-Cy7 Conjugated |
WB |
Mouse |
Rat |
Specifications |
PE-Cy7 |
Rabbit |
KLH conjugated synthetic peptide derived from human Crry |
51-150/559 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
12946 |
Q64735 |
Cell membrane |
Mcp; Crry; mCRY; Complement component receptor 1-like protein; Complement regulatory protein Crry; Protein p65; Cr1l; Cry |
Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Plays a crucial role in early embryonic development by maintaining fetomaternal tolerance. Also acts as a costimulatory factor for T-cells which favors IL-4 secretion. |
Application Dilution |
WB |
1:300-5000 |