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Crry Polyclonal Antibody, PE-Cy7 Conjugated

Applications

  • WB

Reactivity

  • Mouse

Predicted Reactivity

  • Rat
Overview
Catalog # bs-14070R-PE-Cy7
Product Name Crry Polyclonal Antibody, PE-Cy7 Conjugated
Applications WB
Reactivity Mouse
Predicted Reactivity Rat
Specifications
Conjugation PE-Cy7
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Crry
Immunogen Range 51-150/559
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 12946
Swiss Prot Q64735
Subcellular location Cell membrane
Synonyms Mcp; Crry; mCRY; Complement component receptor 1-like protein; Complement regulatory protein Crry; Protein p65; Cr1l; Cry
Background Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Plays a crucial role in early embryonic development by maintaining fetomaternal tolerance. Also acts as a costimulatory factor for T-cells which favors IL-4 secretion.
Application Dilution
WB 1:300-5000