Overview |
bs-13324R-Cy5.5 |
GDI1 Polyclonal Antibody, Cy5.5 Conjugated |
IF(IHC-P), IF(IHC-F), IF(ICC) |
Mouse, Chimpanzee |
Human, Rat, Cow, Sheep, Pig, Rabbit, Zebrafish |
Specifications |
Cy5.5 |
Rabbit |
KLH conjugated synthetic peptide derived from human GDI1 |
1-100/447 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
2664 |
Cytoplasm |
1A; FLJ41411; GDI-1; gdi1; GDIA_HUMAN; GDIL; GDP dissociation inhibitor 1; Guanosine diphosphate dissociation inhibitor 1; Mental retardation X-linked 41; Mental retardation X-linked 48; MRX41; MRX48; Oligophrenin 2; Oligophrenin-2; OPHN2; Protein XAP 4; Protein XAP-4; Protein XAP4; Rab GDI alpha; Rab GDP dissociation inhibitor alpha; RABGD1A; RABGDIA; XAP 4. |
Rab proteins, a family of Ras-related small GTP-binding proteins, play a key role in regulating intracellular vesicle trafficking (1?). Rab GDP dissociation inhibitor (Rab GDI or GDI2) forms a soluble complex with Rab proteins and thereby prevents the exchange of GDP for GTP (1?). In mammals, there exist two major isoforms, Rab GDI alpha (also known as XAP-4) and Rab GDI beta (1,4). While the mammalian Rab GDI beta-genes are ubiquitously expressed, the Rab GDI ?genes are predominantly brain-specific (1). Since it is expressed predominantly in neural and sensory tissues, Rab GDI a may serve a specific function in neural signal transmission (5). The gene sequences for the Rab GDI proteins are extremely conserved in evolution, with substantial homology preserved across three eukaryotic kingdoms (5). |
Application Dilution |
IF(IHC-P) |
1:50-200 |
IF(IHC-F) |
1:50-200 |
IF(ICC) |
1:50-200 |