DYX1C1 Polyclonal Antibody, Cy5.5 Conjugated
A) and a codon (1249G --> T), introduce a premature stop codon and truncate the protein by 4 amino acids. DYX1C1 encodes a nuclear tetratricopeptide repeat domain protein that is dynamically regulated in brain. In human brain, DYX1C1 protein localizes to a fraction of cortical neurons and white matter glial cells. It is also expressed in lung, kidney and testis.", "Category"=>"Conjugated Primary Antibody", "Clonality"=>"Polyclonal", "Concentration"=>"1ug/ul", "Conjugation"=>"Cy5.5", "Cross Reactive Species"=>"Mouse, Rat", "Datasheet URL"=>"https://www.biossusa.com/store/datasheets/bs-13043R-Cy5.5", "Excitation Emission"=>"675nm/694nm", "Gene ID"=>"161582", "Gene ID Link"=>"Entrez Gene: 161582", "Host"=>"Rabbit", "Immunogen Sequence"=>"51-120/420", "Isotype"=>"IgG", "Lead Time"=>"10 to 15 business days.", "Modification"=>"Unmodified", "Predicted Reactivity"=>"Human, Dog, Cow, Chicken, Zebrafish", "Product URL"=>"https://www.biossusa.com/products/bs-13043R-Cy5.5", "Purification"=>"Purified by Protein A.", "Size"=>"100ul", "Source"=>"KLH conjugated synthetic peptide derived from human DYX1C1", "Storage"=>"Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.", "Storage Buffer"=>"Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.", "Storage Condition"=>"Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.", "Subcellular Locations"=>"Cytoplasm, Nucleus", "Synonyms"=>"Dyslexia susceptibility 1 candidate 1; Dyslexia susceptibility 1 candidate gene 1 protein; DYX1; DYX1C1; DYXC1; DYXC1_HUMAN; EKN1; FLJ37882; MGC70618; RD.", "Target Protein"=>"DYX1C1"} -->
Applications
Reactivity
Predicted Reactivity
Overview | |
Catalog # | bs-13043R-Cy5.5 |
Product Name | DYX1C1 Polyclonal Antibody, Cy5.5 Conjugated |
Applications | WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
Reactivity | Mouse, Rat |
Predicted Reactivity | Human, Dog, Cow, Chicken, Zebrafish |
Specifications | |
Conjugation | Cy5.5 |
Host | Rabbit |
Source | KLH conjugated synthetic peptide derived from human DYX1C1 |
Immunogen Range | 51-120/420 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target | |
Gene ID | 161582 |
Subcellular location | Cytoplasm, Nucleus |
Synonyms | Dyslexia susceptibility 1 candidate 1; Dyslexia susceptibility 1 candidate gene 1 protein; DYX1; DYX1C1; DYXC1; DYXC1_HUMAN; EKN1; FLJ37882; MGC70618; RD. |
Background | The gene encoding DYX1C1 maps in the 15q21 region, which is disrupted by a translocation t(2;15)(q11;q21) and segregates with dyslexia. Two sequence changes in DYX1C1, including one involving the translation initiation sequence and an Elk-1 transcription factor binding site (-3G --> A) and a codon (1249G --> T), introduce a premature stop codon and truncate the protein by 4 amino acids. DYX1C1 encodes a nuclear tetratricopeptide repeat domain protein that is dynamically regulated in brain. In human brain, DYX1C1 protein localizes to a fraction of cortical neurons and white matter glial cells. It is also expressed in lung, kidney and testis. |
Application Dilution | |
WB | 1:300-5000 |
IF(IHC-P) | 1:50-200 |
IF(IHC-F) | 1:50-200 |
IF(ICC) | 1:50-200 |