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GDF8/MSTN Polyclonal Antibody, AbBy Fluor® 405 Conjugated

Applications

  • WB
  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Reactivity

  • Human
  • Mouse
  • Rat
  • Pig

Predicted Reactivity

  • Cow
  • Sheep
  • Horse
  • Chicken
Overview
Catalog # bs-1288R-BF405
Product Name GDF8/MSTN Polyclonal Antibody, AbBy Fluor® 405 Conjugated
Applications WB, IF(IHC-P), IF(IHC-F), IF(ICC)
Reactivity Human, Mouse, Rat, Pig
Predicted Reactivity Cow, Sheep, Horse, Chicken
Specifications
Conjugation AbBy Fluor® 405
Host Rabbit
Source KLH conjugated synthetic peptide derived from human GDF8
Immunogen Range 281-375/375
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 2660
Swiss Prot O14793
Subcellular location Secreted
Synonyms GDF8; MSLHP; Growth/differentiation factor 8; GDF-8; Myostatin; MSTN
Background The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth. Acts specifically as a negative regulator of skeletal muscle growth. [SUBUNIT] Homodimer; [TISSUE SPECIFICITY] Expressed specifically in developing and adult skeletal muscle. Weak expression in adipose tissue. Belongs to the TGF-beta family.
Application Dilution
WB 1:300-5000
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200