| Overview |
| bs-12402R-Cy5.5 |
| RBM15/SPEN Polyclonal Antibody, Cy5.5 Conjugated |
| IF(IHC-P), IF(IHC-F), IF(ICC) |
| Human, Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Chicken |
| Specifications |
| Cy5.5 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human RBM15 |
| 151-250/977 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| Nucleus |
| One twenty two protein; OTT; OTT1; SPEN; RNA binding mot protein 15; RBM15_HUMAN. |
| RBM15 is a 977 amino acid protein that localizes to the nucleus and contains one SPOC domain and three RRM domains. Expressed as multiple alternatively spliced isoforms, RBM15 interacts with Epstein-Barr (EBV) viral proteins and is thought to be involved in the regulation of Hox genes, possibly via interactions with RNA and spliceosome components. RBM15 is subject to post-translational phosphorylation, probably by ATM or ATR. Chromosomal aberrations involving the RBM15 gene, which localizes to human chromosome 1, may be associated with the development of acute megakaryoblastic leukemia. |
| Application Dilution |
| IF(IHC-P) |
1:50-200 |
| IF(IHC-F) |
1:50-200 |
| IF(ICC) |
1:50-200 |
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