Get 20% off all conjugated antibody purchases with code "CON-ANTIBODY2025"! Offer valid on direct orders only. Available for US customers and internationally through distributors.

Contact us at 1.800.501.7654 or info@biossusa.com

MenuSearch

CASK Polyclonal Antibody, Cy3 Conjugated

Applications

  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Reactivity

  • Rat

Predicted Reactivity

  • Human
  • Mouse
  • Cow
  • Sheep
  • Pig
  • Horse
  • Chicken
  • Rabbit
Overview
Catalog # bs-11338R-Cy3
Product Name CASK Polyclonal Antibody, Cy3 Conjugated
Applications IF(IHC-P), IF(IHC-F), IF(ICC)
Reactivity Rat
Predicted Reactivity Human, Mouse, Cow, Sheep, Pig, Horse, Chicken, Rabbit
Specifications
Conjugation Cy3
Host Rabbit
Source KLH conjugated synthetic peptide derived from human CASK
Immunogen Range 651-750/926
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Subcellular location Cytoplasm, Nucleus, Cell membrane
Synonyms CAGH39; Caki; Calcium/calmodulin dependent serine protein kinase; Calcium/calmodulin dependent serine protein kinase MAGUK family; Calcium/calmodulin dependent serine protein kinase membrane associated guanylate kinase; Calcium/calmodulin-dependent serine protein kinase; CAMGUK; CAMGUK protein; CAMGUK, drosophila, homolog of antibody casK; CMG; CSKP_HUMAN; DXPri1; DXRib1; FGS4; hCASK; LIN 2; Lin 2 homolog; LIN2 antibody Lin2 homolog; MICPCH; MRXSNA; Pals3; Peripheral plasma membrane protein CASK; Protein lin-2 homolog; TNRC8; Trinucleotide repeat containing 8; Vertebtate LIN2 homolog.
Background The MAGUK (membrane-associated guanylate kinase homologs) family of proteins contain multiple protein-binding domains and are involved in cell junction organization, tumor suppression, and signaling. CASK (also designated LIN-2) belongs to a MAGUK subfamily which is characterized by a novel domain structure that consists of a calcium/calmodulin- dependent protein kinase domain followed by PDZ, SH3 and guanylate kinase-like (GUK) domains. CASK is expressed in rat brain where it binds to cell-surface proteins, such as neurexin and syndecan, and is thought to be involved in signaling at neuronal synapses. CASK translocates to the nucleus and interacts with Tbr-1 to form a complex, which binds to a specific DNA sequence (the T-element), and induces the expression of specific genes, including Reelin. CASK displays a transcription regulation function, which appears crucial for cerebrocortical development.
Application Dilution
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Search our catalog of hundreds of thousands of products