Overview |
bs-11235R-APC-Cy5 |
GRK4+5+6 Polyclonal Antibody, APC-Cy5 Conjugated |
IF(IHC-P), IF(IHC-F), IF(ICC) |
Human, Mouse, Rat, Dog, Cow, Pig, Rabbit |
Specifications |
APC-Cy5 |
Rabbit |
KLH conjugated synthetic peptide derived from human GRK6 |
181-280/576 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
2868, 2869, 2870 |
Cell membrane |
GRK4: G protein-coupled receptor kinase 4, G protein-coupled receptor kinase GRK4, GPRK2L, GPRK4
GRK5: G protein-coupled receptor kinase 5, G protein-coupled receptor kinase GRK5, GPRK5
GRK6: G protein-coupled receptor kinase 6, G protein-coupled receptor kinase GRK6, GPRK6 |
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their down-regulation. |
Application Dilution |
IF(IHC-P) |
1:50-200 |
IF(IHC-F) |
1:50-200 |
IF(ICC) |
1:50-200 |