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Sidekick 1 Polyclonal Antibody, PE-Cy5 Conjugated

Applications

  • FCM

Reactivity

  • Human

Predicted Reactivity

  • Mouse
  • Rat
  • Sheep
  • Pig
  • Horse
Overview
Catalog # bs-11164r-pe-cy5-100ul
Product Name Sidekick 1 Polyclonal Antibody, PE-Cy5 Conjugated
Applications FCM
Reactivity Human
Predicted Reactivity Mouse, Rat, Sheep, Pig, Horse
Specifications
Conjugation PE-Cy5
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Sidekick 1
Immunogen Range 1501-1600/2213
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Subcellular location Cell membrane
Synonyms FLJ31425; Protein sidekick-1; sdk1; SDK1_HUMAN; sidekick 1 antibody Sidekick homolog 1, cell adhesion molecule chicken; sidekick1.
Background Cell adhesion molecules influence cell growth, differentiation, embryogenesis, immune response and cancer metastasis by networking information from the extracellular matrix to the cell. Sidekick-1 (SDK1) is a 2,213 amino acid single-pass membrane protein that functions as a cell adhesion molecule by guiding axonal terminals to specific synapses in developing neurons. Existing as three alternatively spliced isoforms, Sidekick-1 is expressed in retinal neurons and contains thirteen fibronectin type-III domains and six Ig-like C2-type (immunoglobulin-like) domains. Sidekick-1 expression is upregulated in glomeruli of patients with HIV-associated nephropathy, where it leads to podocyte dysfunction. The gene encoding Sidekick-1 maps to human chromosome 7p22.2 and murine chromosome 5 G2.
Application Dilution
FCM 1:20-100