Overview |
bs-11102R |
Neprilysin 2 Polyclonal Antibody |
WB, ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC), ICC |
Human, Mouse, Rat, Dog |
Specifications |
Unconjugated |
Rabbit |
KLH conjugated synthetic peptide derived from human Neprilysin 2 |
451-550/779 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target |
79258 |
Q495T6 |
Secreted, Cell membrane |
NL1; NL2; SEP; NEP2; MMEL2; NEPII; Membrane metallo-endopeptidase-like 1; Membrane metallo-endopeptidase-like 2; NEP2(m); Neprilysin II; Neprilysin-2; MMEL1; MELL1 |
Metalloprotease involved in sperm function, possibly by modulating the processes of fertilization and early embryonic development. Degrades a broad variety of small peptides with a preference for peptides shorter than 3 kDa containing neutral bulky aliphatic or aromatic amino acid residues. Shares the same substrate specificity with MME and cleaves peptides at the same amide bond (By similarity). |
Application Dilution |
WB |
1:300-5000 |
ELISA |
1:500-1000 |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |
IF(IHC-P) |
1:50-200 |
IF(IHC-F) |
1:50-200 |
IF(ICC) |
1:50-200 |
ICC |
1:100-500 |