Overview |
bs-10166R-Biotin |
KDM1 Polyclonal Antibody, Biotin Conjugated |
WB, ELISA |
Human, Mouse, Rat |
Dog, Cow, Pig, Chicken, Rabbit |
Specifications |
Biotin |
Rabbit |
KLH conjugated synthetic peptide derived from human KDM1 |
301-400/852 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
Nucleus |
Amine oxidase flavin containing domain 2; Amine oxidase flavin containing domain 2; Amine oxidase flavin containing domain protein 2; AOF 2; AOF2; BHC110; BRAF35 HDAC complex protein BHC110; BRAF35-HDAC complex protein BHC110; FAD binding protein BRAF35 HDAC complex, 110 kDa subunit; Flavin containing amine oxidase domain containing protein 2; Flavin-containing amine oxidase domain-containing protein 2; KDM 1; Kdm1a; KDM1A_HUMAN; KIAA0601; LSD 1; LSD1; Lysine K specic demethylase 1; Lysine K specic demethylase 1A; Lysine specic histone demethylase 1; Lysine specic histone demethylase 1A; Lysine-specic histone demethylase 1; Lysine-specic histone demethylase 1A. |
Gene activation and repression is specifically regulated by histone methylation status at distinct lysine residues. Lysine specific demethylase 1 (KDM1/LSD1) is a long-sought histone demethylase that specifically demethylates mono and di methyl histone H3 at K4 and K9. Thus KDM1 is a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. |
Application Dilution |
WB |
1:300-5000 |
ELISA |
1:500-1000 |