| Overview |
| bs-0127R-PE |
| Bax Polyclonal Antibody, PE Conjugated |
| WB, FCM |
| Human, Mouse, Rat, Bovine, Pig, Chicken, Rabbit, Zebrafish |
| Dog, Cow, Sheep |
| Specifications |
| PE |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Bax |
| 84-175/192 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 581 |
| Q07812 |
| Cytoplasm, Cell membrane |
| BCL2L4; Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4; BAX |
| Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. |
| Application Dilution |
| WB |
1:300-5000 |
| FCM |
1:20-100 |
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