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Tau Protein(Thr181) Polyclonal Antibody, HRP Conjugated

Applications

  • WB
  • IHC-P
  • IHC-F

Reactivity

  • Human
Overview
Catalog # bs-23383R-HRP
Product Name Tau Protein(Thr181) Polyclonal Antibody, HRP Conjugated
Applications WB, IHC-P, IHC-F
Reactivity Human
Specifications
Conjugation HRP
Host Rabbit
Source KLH conjugated synthetic peptide derived from human phospho-Tau Protein Thr181
Modification Site Thr181
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20¡C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 4137
Swiss Prot P10636
Synonyms Tau (phospho T181); p-Tau (phospho T181); Tau(Phospho-Thr181); MAPT(phospho T181); p-Tau(Thr181); MAPT; Microtuble-associted protein Tau; AI413597; AW045860; DDPAC; Disinhibition dementia parkinsonism amyotrophy complex; FLJ31424; FTDP 17; FTDP17; G Protein beta 1 gamma 2 subunit interacting factor 1; G protein beta1/gamma2 subunit interacting factor 1; MAPTL; MGC134287; MGC138549; MGC156663; Microtubule associated protein tau isoform 4; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; Paired helical filament tau; PHF tau; PHF-tau; PPND; pTau; RNPTAU; Tauopathy and respiratory failure, included; TAU_HUMAN.
Background Tau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.
Application Dilution
WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500