Overview |
bs-6058R-Biotin |
Nicastrin Polyclonal Antibody, Biotin Conjugated |
WB, ELISA, IHC-P, IHC-F |
Mouse |
Human, Rat, Cow, Pig, Horse, Chicken |
Specifications |
Biotin |
Rabbit |
KLH conjugated synthetic peptide derived from human Nicastrin |
21-120/709 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
23385 |
Q92542 |
Cell membrane |
ATAG1874; Nicastrin; NCSTN; KIAA0253; UNQ1874/PRO4317 |
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex. |
Application Dilution |
WB |
1:300-5000 |
ELISA |
1:500-1000 |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |