Overview |
bs-2792R-Cy7 |
CRHR2 Polyclonal Antibody, Cy7 Conjugated |
WB, IF(IHC-F), IF(ICC) |
This antibody may cross react with CRHR1. |
Human, Mouse |
Rat, Dog, Cow, Pig, Horse, Chicken, Rabbit |
Specifications |
Cy7 |
Rabbit |
KLH conjugated synthetic peptide derived from human CRHR2 |
51-150/411 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
1395 |
Q13324 |
Cell membrane |
CRF2; CRFR2; CRF-RB; HM-CRF; Corticotropin-releasing factor receptor 2; CRF-R-2; CRF-R2; CRFR-2; Corticotropin-releasing hormone receptor 2; CRH-R-2; CRH-R2; CRHR2; CRF2R; CRH2R |
G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. |
Application Dilution |
WB |
1:300-5000 |
IF(IHC-F) |
1:50-200 |
IF(ICC) |
1:50-200 |