| Overview |
| bs-20373R-RBITC |
| IL-10 Polyclonal Antibody, RBITC Conjugated |
| WB, FCM |
| Human, Mouse, Rat |
| Specifications |
| RBITC |
| Rabbit |
| KLH conjugated synthetic peptide derived from human IL-10 |
| 51-100/178 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 3586 |
| P22301 |
| Secreted |
| CSIF; TGIF; GVHDS; IL-10; IL10A; Interleukin-10; Cytokine synthesis inhibitory factor; IL10 |
| Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. IL-10 Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. |
| Application Dilution |
| WB |
1:300-5000 |
| FCM |
1:20-100 |
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