| Overview |
| bs-2093R-APC-Cy5.5 |
| Integrin alpha 3 Polyclonal Antibody, APC-Cy5.5 Conjugated |
| WB, FCM |
| Mouse, Pig |
| Human, Rat |
| Specifications |
| APC-Cy5.5 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Integrin alpha 3 |
| 976-1025/1051 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 3675 |
| P26006 |
| Cell membrane |
| VL3A; CD49C; GAPB3; ILNEB; MSK18; VCA-2; VLA3a; GAP-B3; Integrin alpha-3; CD49 antigen-like family member C; FRP-2; Galactoprotein B3; VLA-3 subunit alpha; ITGA3 |
| Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. |
| Application Dilution |
| WB |
1:300-5000 |
| FCM |
1:20-100 |
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