Overview |
bs-2016R-BF750 |
Integrin Alpha V + Beta1 Antibody, AbBy Fluor® 750 Conjugated |
WB, FCM, IF(ICC) |
Human, Mouse, Rat |
Dog, Cow, Sheep, Pig, Horse |
Specifications |
AbBy Fluor® 750 |
Rabbit |
Mixed KLH conjugated syntheticpeptides for human Integrin Alpha V and human Integrin Beta1 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
3685, 3688 |
Cytoplasm, Secreted |
Integrin alpha-V: Integrin alpha-V, Vitronectin receptor subunit alpha, CD51
Integrin beta-1: Fibronectin receptor subunit beta, Glycoprotein IIa, GPIIA, VLA-4 subunit beta, CD29 |
The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform 2 interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro). |
Application Dilution |
WB |
1:300-5000 |
FCM |
1:20-100 |
IF(ICC) |
1:50-200 |