Overview |
bs-1969R-HRP |
LAMA3/Laminin 5 alpha 3 Antibody, HRP Conjugated |
ELISA, IHC-P |
Human |
Mouse, Rat |
Specifications |
HRP |
Rabbit |
KLH conjugated synthetic peptide derived from human LAMA3 |
2701-2800/3333 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
3909 |
Q16787 |
Secreted, Cell membrane, Extracellular matrix |
E170; LOCS; BM600; LAMNA; Laminin subunit alpha-3; Epiligrin 170 kDa subunit; Epiligrin subunit alpha; Kalinin subunit alpha; Laminin-5 subunit alpha; Laminin-6 subunit alpha; Laminin-7 subunit alpha; Nicein subunit alpha; LAMA3 |
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminin-5 is thought to be involved in (1) cell adhesion via integrin alpha-3/beta-1 in focal adhesion and integrin alpha-6/beta-4 in hemidesmosomes, (2) signal transduction via tyrosine phosphorylation of pp125-FAK and p80, (3) differentiation of keratinocytes. |
Application Dilution |
ELISA |
1:500-1000 |
IHC-P |
1:200-400 |