Overview |
bs-1356R-APC-Cy7 |
Integrin Alpha V + Beta 5 Antibody, APC-Cy7 Conjugated |
FCM, IF(IHC-P), IF(IHC-F), IF(ICC) |
Human, Mouse |
Rat |
Specifications |
APC-Cy7 |
Rabbit |
KLH conjugated synthetic peptide derived from human Integrin beta 5 and Integrin alpha V |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
3685 |
P06756 |
Cell membrane |
CD51; MSK8; VNRA; VTNR; Integrin alpha-V; Vitronectin receptor subunit alpha; ITGAV |
The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. |
Application Dilution |
FCM |
1:20-100 |
IF(IHC-P) |
1:50-200 |
IF(IHC-F) |
1:50-200 |
IF(ICC) |
1:50-200 |