| Overview |
| bs-1252R-PE-Cy7 |
| API5 Polyclonal Antibody, PE-Cy7 Conjugated |
| WB, FCM |
| Mouse |
| Human, Rat, Dog, Cow, Pig, Horse, Guinea Pig |
| Specifications |
| PE-Cy7 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human API5 |
| 351-460/504 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 8539 |
| Q9BZZ5 |
| Cytoplasm, Nucleus |
| AAC11; AAC-11; Apoptosis inhibitor 5; API-5; Antiapoptosis clone 11 protein; Cell migration-inducing gene 8 protein; Fibroblast growth factor 2-interacting factor; FIF; Protein XAGL; API5; MIG8 |
| Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. |
| Application Dilution |
| WB |
1:300-5000 |
| FCM |
1:20-100 |
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