GRL-0617
| Overview | |
| Catalog # | bs-83075c-5-mg |
| Product Name | GRL-0617 |
| Specifications | |
| Storage Buffer | Off-white solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | GRL-0617 is a potent (IC50 = 600 nM) noncovalent inhibitor of severe acute respiratory syndrome-coronavirus papain-like protease (SARS-CoV PLpro). GRL0617 inhibited SARS-CoV viral replication in Vero E6 cells with no cytotoxicity (EC50 = 15 µM). Inactive against human DUB-like proteases HAUSP, USP18, UCH-L1, UCH-L3, and PLP2. |
| Description | CAS Number: 1093070-16-6 Chemical Name: 5-Amino-2-methyl-N-(1R-naphthalen-1-yl-ethyl)benzamide Molecular weight: 304.39 Formula: C20H20N2O Solubility: DMSO (>30 mg/ml) Ethanol (>15 mg/ml) Physical Properties: Beige solid Purity: 99% by HPLC NMR (Conforms) |
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