GSK872
| Overview | |
| Catalog # | bs-83050c-5-mg |
| Product Name | GSK872 |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | GSK872 is a potent (IC50 = 1.8nM domain binding; IC50 = 1.3 nM kinase activity) and selective inhibitor of receptor interacting protein 3 (RIP3).1 It is able to prevent necroptosis, virus-induced necrosis, and TLR3-induced necrosis.1,2 GSK872 can induce Caspase8-mediated apoptosis at higher concentrations (e.g.3 µM).2 |
| Description | CAS Number: 1346546-69-7 Chemical Name: N-(6-Propan-2-ylsulfonylquinolin-4-yl)-1,3-benzothiazol-5-amine Molecular weight: 383.49 Formula: C19H17N3O2S2 Solubility: DMSO (>25 mg/ml) Physical Properties: Off-white or pale yellow solid Purity: 98% by HPLC NMR (Conforms) |
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