SNS-314 mesylate
| Overview | |
| Catalog # | bs-83015c-5-mg |
| Product Name | SNS-314 mesylate |
| Specifications | |
| Storage Buffer | Off-white solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | SNS-314 is a potent and selective pan-Aurora kinase inhibitor (IC50’s: Aurora A = 9 nM, Aurora B = 31 nM, Aurora C = 3 nM.1,2 It was able to inhibit proliferation in a wide panel of human cancer cell lines including colon (HCT116), breast (MDA-MB-231), prostate (PC-3), lung (H1299, Calu-6), ovarian (A2780), melanoma (A375) and liver (SMMC-7721, HepG2, LM6).1-4 |
| Description | CAS Number: 1146618-41-8 Chemical Name: 1-(3-Chlorophenyl)-3-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl]urea mesylate Molecular weight: 527.04 Formula: C18H15ClN6OS2·CH3SO3H Solubility: DMSO (>25 mg/ml) Physical Properties: Off-white solid Purity: 98% by HPLC NMR (conforms) |
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