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iGP-1

Overview
Catalog # bs-83005c-5-mg
Product Name iGP-1
Specifications
Storage Buffer Off-white to pale orange solid
Storage Condition -20°C
Target
Product Information A potent and cell permeable inhibitor of the mitochondrial glycerol-3-phosphate dehydrogenase (mGPDH), IC50=6.3 M, which is selective over the cytosolic enzyme1. It does not block pyruvate uptake into cells or mitochondria and has no direct effect on glycolysis in synaptosomes. This novel inhibitor is a unique tool which may be used to investigate the role of glycerol-3-phosphate metabolism in isolated and intact systems.1
Description CAS Number: 27031-00-1

Chemical Name: N-[4-(1H-Benzoimidazol-2-yl)-phenyl]-succinamic acid

Molecular weight: 309.32

Formula: C17H15N3O3

Solubility: DMSO (50 mg/ml)

Physical Properties: Beige solid

Purity: 98% by TLC NMR (Conforms)