Luminespib

Overview
Catalog #	bs-82980c-5-mg
Product Name	Luminespib
Specifications
Storage Buffer	White or off-white solid
Storage Condition	-20°C
Target
Product Information	Luminespib is a potent inhibitor (IC50 = 21 nM) of HSP90.1 It is active against various human tumor xenograft models acting via several processes including cytostasis, apoptosis, invasion, and angiogenesis.2,3 Luminespib enhances tumor susceptibility to T-cell-based immunotherapy by re-invigorating the cancer-immunity cycle in NANOG+ cancer cells.4 It also acts as a radiosensitizer against various tumor cells.5-7
Description	CAS Number: 747412-49-3 Chemical Name: 5-(2,4-Dihydroxy-5-propan-2-ylphenyl)-N-ethyl-4-[4-(morpholin-4-ylmethyl)phenyl]-1,2-oxazole-3-carboxamide Molecular weight: 465.54 Formula: C26H31N3O5 Solubility: DMSO (>25 mg/ml) Physical Properties: White solid Purity: >99% by HPLC NMR (Conforms)