NS 1619

Overview
Catalog #	bs-82963c-5-mg
Product Name	NS 1619
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	NS 1619 is a selective activator of large conductance Ca(2+)-dependent potassium channels (BKCa or KCa1.1).1,2 It was able to increase blood-brain tumor barrier permeability in rat brain tumor models.3,4 NS 1619 inhibited proliferation and induced apoptosis in A2780 ovarian cancer cells.5 Displays cardioprotective effects in an ischemia-reperfusion model6 and neuroprotective effects in a traumatic brain injury model7.
Description	CAS Number: 153587-01-0 Chemical Name: 1-(2-Hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzo[d]imidazole-2(3H)-one Molecular weight: 362.23 Formula: C15H8F6N2O2 Solubility: DMSO (>25 mg/ml) Physical Properties: White solid Purity: 98% by TLC NMR (Conforms)