BIIB021

Overview
Catalog #	bs-82962c-5-mg
Product Name	BIIB021
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	Potent HSP90 inhibitor (IC50 = 30 nM HER-2 degradation).1 It inhibited the proliferation of MCF7 and BT474 breast cancer cell lines (IC50 = 100 nM for each). BIIB021 has shown efficacy as a therapeutic in multiple cancer models.2-5
Description	CAS Number: 848695-25-0 Chemical Name: 6-Chloro-9-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]purin-2-amine Molecular weight: 318.76 Formula: C14H15ClN6O Solubility: DMSO (>25 mg/ml) Physical Properties: White solid Purity: 98% by HPLC NMR (Conforms)