Azoramide
| Overview | |
| Catalog # | bs-82957c-10-mg |
| Product Name | Azoramide |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Azoramide is a modulator of the unfolded protein response (UPR).1 It improves endoplasmic reticulum (ER) protein folding and activates ER chaperone capacity to protect cells against ER stress. It displayed potent anti-diabetic activity in two mouse models by improving insulin sensitivity and pancreatic β cell function. Azoramide increased SERCA expression leading to enhanced calcium retention in the ER indicating calcium homeostasis as a possible mechanism for its anti-diabetic acitivty. |
| Description | CAS Number: 932986-18-0 Chemical Name: N-[2-[2-(4-Chlorophenyl)-4-thiazolyl]ethyl]butanamide Molecular weight: 308.83 Formula: C15H17ClN2OS Solubility: DMSO (>25 mg/ml) Ethanol (>25 mg/ml) Physical Properties: Off-white solid Purity: 98% by TLC, NMR (Conforms) |
Powered by Bioz