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N-Acetyl-S-farnesyl-L-cysteine

Overview
Catalog # bs-82947c-5-mg
Product Name N-Acetyl-S-farnesyl-L-cysteine
Specifications
Storage Buffer Pale yellow solid
Storage Condition -20°C
Target
Product Information N-Acetyl-S-farnesyl-L-cysteine (AFC) inhibits S-farnesylcysteine methyl transferase (Km = 20 µM).1 AFC blocked capacitative Ca2+ influx in human embryonic kidney 293 cells2 and store-regulated Ca2+ entry in human platelets3. Topical AFC has been shown to inhibit neutrophil chemotaxis and other inflammatory responses without systemic effects.4,5
Description CAS Number: 135304-07-3

Chemical Name: 2-Acetamido-3-(3,7,11-trimethyldodeca-2,6,10-trienylsulfanyl)propanoic acid

Molecular weight: 367.55

Formula: C20H33NO3S

Solubility: DMSO (25 mg/ml) Ethanol (25 mg/ml)

Physical Properties: Yellow oil

Purity: 98% by TLC, NMR (Conforms)