Rbin-1
Overview | |
Catalog # | bs-82943c-5-mg |
Product Name | Rbin-1 |
Specifications | |
Storage Buffer | Tan Solid |
Storage Condition | -20°C |
Target | |
Product Information | Rbin-1 is potent (GI50 = 136 nM) and reversible inhibitor of eukaryotic ribosome assembly. The biochemical target of Rbin-1 is Midasin (Mdn1), an essential AAA+ protein. Blocking of Mdn1 by Rbin-1 inhibits the processing of pre-60S particles, important pre-ribosomal subunits produced in the nucleolus. |
Description | CAS Number: 328023-11-6 Chemical Name: 3-[(2-Methyl-2-propen-1-yl)sulfanyl]-5H-[1,2,4]triazino[5,6-b]indole Molecular weight: 256.33 Formula: C13H12N4S Solubility: DMSO (>25 mg/ml) Physical Properties: Pale yellow solid Purity: >98% by TLC, NMR (Conforms) |