4th of July Flash Sale! 25% off your order with code "Freedom25" - Valid 6/24/24-7/5/24 For U.S. Customers and Direct Orders Only

Rbin-1

Overview
Catalog # bs-82943c-5-mg
Product Name Rbin-1
Specifications
Storage Buffer Tan Solid
Storage Condition -20°C
Target
Product Information Rbin-1 is potent (GI50 = 136 nM) and reversible inhibitor of eukaryotic ribosome assembly. The biochemical target of Rbin-1 is Midasin (Mdn1), an essential AAA+ protein. Blocking of Mdn1 by Rbin-1 inhibits the processing of pre-60S particles, important pre-ribosomal subunits produced in the nucleolus.
Description CAS Number: 328023-11-6

Chemical Name: 3-[(2-Methyl-2-propen-1-yl)sulfanyl]-5H-[1,2,4]triazino[5,6-b]indole

Molecular weight: 256.33

Formula: C13H12N4S

Solubility: DMSO (>25 mg/ml)

Physical Properties: Pale yellow solid

Purity: >98% by TLC, NMR (Conforms)