gamma-L-Glutamyl-p-nitroanilide HCl
| Overview | |
| Catalog # | bs-82927c-100-mg |
| Product Name | gamma-L-Glutamyl-p-nitroanilide HCl |
| Specifications | |
| Storage Buffer | white solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | L-γ-Glutamyl-p-nitroanilide (GPNA) is a substrate for γ-glutamyl transpeptidase. GPNA is used for the determination of γ-glutamyl transpeptidase hydrolytic activity via spectrophotometric monitoring of p-nitroaniline released by the action of the enzyme on GPNA.1 GPNA has also been shown to be an inhibitor of glutamine uptake – solute-linked carrier family A1 member 5 (SLC1A5)2 Cellular uptake of L-glutamine (regulated by SLC1A5) is a rate-limiting step that activates mTOR and is, thus, an interesting cancer chemotherapy target.3 |
| Description | CAS Number: 67953-08-6 Chemical Name: Molecular weight: 303.70 Formula: C11H13N3O5 · HCl Solubility: Water (5 mg/ml) Physical Properties: Off-white solid Purity: 98% |
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