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27-Hydroxycholesterol

Overview
Catalog # bs-82902c-1-mg
Product Name 27-Hydroxycholesterol
Specifications
Storage Buffer White solid
Storage Condition -20°C
Target
Product Information Metabolite resulting from the action of sterol 27-hydroxylase on cholesterol. Concentrations of 27-hydroxycholesterol are elevated in patients with Alzheimers disease and mild cognitive impairment.1,2 Endogenous selective estrogen receptor modulator3 and ligand for the liver X receptor(EC50 = 85nM for LXRα and 71nM for LXRβ)4.
Description CAS Number: 20380-11-4

Chemical Name: 27-Hydroxycholesterol; 5,25R-Cholesten-3β,26-diol

Molecular weight: 402.66

Formula: C27H46O2

Solubility: DMSO (10 mg/ml) Ethanol (10 mg/ml)

Physical Properties: White solid

Purity: 98% by HPLC, NMR (Conforms)