S1RA

Overview
Catalog #	bs-82821c-5-mg
Product Name	S1RA
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	S1RA (E-52862) is a potent and selective 1 antagonist with weak binding at 2 (IC50’s: 1 = 17nM, 2 = 9300nM).1,2 S1RA abolished mechanical and thermal hyperalgesia in mice with carrageenan-induced acute inflammation by enhancing the action of endogenous opioid peptides of immune origin in a 1 dependent manner.3 BD1063 potentiated µ-opioid antinociception in mice in a -dependent manner.4 S1RA displayed neuroprotective effects in a mouse model of ischemic stroke.5
Description	CAS Number: 1265917-14-3 Chemical Name: 4-{2-[5-Methyl-1-(napthalen-2-yl)-1H-pyrazol-3-yloxy]ethyl}morpholine hydrochloride Molecular weight: 373.88 Formula: C20H23N3O2·HCl Solubility: DMSO (>25 mg/ml) Physical Properties: Off-white solid Purity: 98% by HPLC NMR (Conforms)