A-438079 HCl
| Overview | |
| Catalog # | bs-82782c-5-mg |
| Product Name | A-438079 HCl |
| Specifications | |
| Storage Buffer | Yellow solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | A-438079 (899431-18-6) is a competitive P2X7 receptor antagonist (pIC50 = 6.9).1 Displayed antinociceptive effects in a rat model of neuropathic pain.2 A-438079 prevented the LPS-induced release of IL-1ß and attenuated LPS-induced (via intrathecal lumbar injection) mechanical hyperalgesia in rat hindpaws.3 It prevented mechanical hyperalgesia following peripheral nerve injury.4 A-438079 protected against cerebral ischemia/reperfusion injury in a rat model via reduction of the neuroinflammatory response.5 |
| Description | CAS Number: 899431-18-6 Chemical Name: 3-[5-(2,3-Dichlorophenyl)tetrazol-1-ylmethyl]pyridine hydrochloride Molecular weight: 342.61 Formula: C13H9Cl2N5 HCl Solubility: DMSO (>25 mg/ml) Physical Properties: White or off-white solid Purity: 98% by HPLC NMR (Conforms) |
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