PFI-3

Overview
Catalog #	bs-82772c-5-mg
Product Name	PFI-3
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	PFI-3 (1819363-80-8) is a selective inhibitor of family VIII bromodomains PB1(5), SMARCA2, and SMARCA4.1 It showed complete selectivity over all non-family VIII bromodomains. PFI-3 blocked adipogenesis in C3H10T1/2 mesenchymal cells at 20µM.Treatment of embryonic stem cells with PFI-3 led to deprivation of stemness and deregulated lineage specificity. Differentiation of trophoblast stem cells in the presence of PFI-3 was enhanced.2 Cell permeable.
Description	CAS Number: 1819363-80-8 Chemical Name: (2E)-1-(2-Hydroxyphenyl)-3-[(1R,4R)-5-(pyridine-2-yl)-2,5-diazabicyclo{2.2.1]heptan-2-yl]prop-2-en-1-one Molecular weight: 321.37 Formula: C19H19N3O2 Solubility: DMSO (>25 mg/ml) Physical Properties: Yellow solid Purity: 98%, NMR (Conforms)