EPZ015666

Overview
Catalog #	bs-82770c-5-mg
Product Name	EPZ015666
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	EPZ015666 is a selective and potent (IC50 = 22nM) inhibitor of arginine methyltransferase 5 (PRMT5).1,2 PRMT5 inhibition with EPZ015666 potently suppressed in vivo glioblastoma tumors3 and significantly inhibited the growth of multiple myeloma cell lines4.
Description	CAS Number: 1616391-65-1 Chemical Name: (S)-N-(3-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-6-(oxetan-3-ylamino)pyrimidine-4-carboxamide Molecular weight: 383.44 Formula: C20H25N5O3 Solubility: DMSO (20 mg/ml) Physical Properties: White solid Purity: 98% by HPLC NMR (conforms)