Eltrombopag
Overview | |
Catalog # | bs-82709c-5-mg |
Product Name | Eltrombopag |
Specifications | |
Storage Buffer | Pale yellow solid |
Storage Condition | -20°C |
Target | |
Product Information | A novel, orally active, small molecule human thrombopoietin receptor (TPO-R) agonist, EC50=0.27 M.1,2 Maintains human hematopoietic stem and progenitor cells under inflammatory conditions.3 Promotes DNA repair in human hematopoietic stem and progenitor cells.4 Acts as a powerful chelator of cellular and extracellular iron(III).5 Stimulates hematopoietic stem cells via a TPO-R-independent mechanism involving iron chelation.6 |
Description | CAS Number: 496775-61-2 Chemical Name: 3’-[2-[(2Z)-1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2’-hydroxy-[1,1’-biphenyl]-3-carboxylic acid Molecular weight: 442.47 Formula: C25H22N4O4 Solubility: DMSO (55 mg/ml) Ethanol (14 mg/ml) Physical Properties: Orange solid Purity: 98% by TLC NMR (Conforms) |